Traveling From Atlanta, GA to Knoxville, TN: Routes, Stops, and Local Tips

The trip from Atlanta, Georgia to Knoxville, Tennessee is a popular route for weekend getaways, college visits, business travel, and outdoor adventures in the Smoky Mountains. Whether you live in Atlanta or you’re visiting and planning a side trip, knowing your options makes the journey smoother and more enjoyable.

This guide walks through how to get from Atlanta to Knoxville, the best driving routes, bus and flight options, and practical tips tailored specifically to people starting in or around Atlanta.

How Far Is Atlanta, GA to Knoxville, TN?

The driving distance from Atlanta to Knoxville is typically:

  • About 200–215 miles, depending on your exact starting point in Atlanta and chosen route
  • Around 3.5–4 hours of drive time in normal traffic

Your actual travel time will vary based on:

  • Atlanta traffic (especially around Downtown, Midtown, and the I‑285 Perimeter)
  • Time of day and day of the week
  • Weather conditions in North Georgia and East Tennessee, especially in winter or during heavy rain

Best Driving Routes From Atlanta to Knoxville

If you’re driving from Atlanta, GA to Knoxville, TN, you have two main routes most locals consider.

1. Fastest & Most Direct: I‑75 North to I‑40 East

This is the most common and straightforward route.

Basic route:

  1. Get on I‑75 North from Atlanta
  2. Continue through Marietta, Kennesaw, Cartersville, and Calhoun
  3. Stay on I‑75 into Chattanooga, TN
  4. From Chattanooga, take I‑24 East briefly and then connect to I‑75 North again
  5. Near Loudon, merge onto I‑40 East toward Knoxville

Why Atlanta drivers like this route:

  • Usually the fastest option
  • Easy interstate driving—good for families and first-time visitors
  • Plenty of rest stops, gas stations, and food options along I‑75

Potential downsides:

  • Congestion leaving Atlanta via I‑75/I‑85 Downtown Connector and around Cobb County
  • Heavier truck traffic, especially between Cartersville and Chattanooga

2. Scenic & Mountain Route: Via US‑441 / Great Smoky Area (For Side Trips)

Some travelers choose a more scenic route that can tie in with the North Georgia mountains or Smoky Mountains. While this isn’t the default choice for a simple Atlanta–Knoxville run, it’s useful if you:

  • Want to visit Helen, GA, Dahlonega, or Blue Ridge
  • Plan to explore Great Smoky Mountains National Park on your way

This involves a mix of state highways and US routes, and usually takes longer than the interstate route. It’s better suited to leisure travel than quick trips.

Quick Route Comparison (From an Atlanta Perspective)

OptionMain RoadsApprox. Time*Best ForThings to Know
I‑75 N → I‑40 EI‑75, I‑24, I‑403.5–4 hoursMost drivers, business trips, first-timersMost direct, easiest to navigate; watch Atlanta & Chattanooga traffic
Scenic / Mountain RouteMixed US & state highways4.5–6+ hoursSightseeing, mountain stopsSlower, more curves; great for day-trip style travel

*Times assume typical conditions leaving from central Atlanta. Traffic and weather can significantly affect travel time.

When Is the Best Time to Drive From Atlanta to Knoxville?

Leaving Atlanta, GA at the right time can make a big difference:

  • Early morning (5–7 a.m.)

    • Often the easiest for beating rush hour
    • Good for same-day check-in at Knoxville hotels or university visits
  • Late morning to early afternoon (10 a.m.–1 p.m.)

    • Avoids both the Atlanta morning rush and much of Knoxville’s afternoon traffic
    • Popular timing for weekend travelers
  • Avoid, if possible:

    • Weekday morning rush (6:30–9:30 a.m.) leaving Atlanta
    • Weekday evening rush (3:30–7 p.m.) around Downtown, Midtown, I‑285 interchanges, and Cobb County

If you’re starting from areas like Sandy Springs, Buckhead, Decatur, or the Airport area, build in extra time to get onto I‑75 North.

Driving Logistics for Atlanta Residents and Visitors

Where You’ll Likely Start in Atlanta

Common starting points within Atlanta include:

  • Downtown / Midtown – easy access to I‑75/85 and then onto I‑75 North
  • Hartsfield-Jackson Atlanta International Airport – connect to I‑85 North, then the Downtown Connector, then I‑75 North
  • Buckhead, Sandy Springs, or Brookhaven – typically join I‑75 via I‑285 or GA‑400 → I‑285 → I‑75
  • Eastside areas like Decatur, East Atlanta, or Kirkwood – reach I‑75 via the Downtown Connector or I‑20 → I‑75

Plan your route using a navigation app, but be ready for Atlanta lane changes and merges, especially around:

  • Downtown Connector (I‑75/85)
  • I‑285 interchanges
  • Cobb Cloverleaf (I‑75 and I‑285)

Rest Stops and Good Places to Break the Trip

From Atlanta to Knoxville via I‑75, typical stopping points include:

  • Cartersville, GA – Food, fuel, and basic services
  • Dalton, GA – Common halfway stretch for a quick meal or gas
  • Chattanooga, TN – If you want a longer break, scenic riverfront and more dining options

This is especially useful if you’re traveling with kids, pets, or older family members.

Taking a Bus From Atlanta, GA to Knoxville, TN

If you’d rather not drive, bus service between Atlanta and Knoxville is a practical option.

Typical Bus Options

  • Buses usually run from Atlanta to Knoxville with at least one stop, often in or near Chattanooga.
  • Travel times are commonly around 4.5–6 hours, depending on route and layovers.

Bus Terminals & Common Departure Points in Atlanta

If you’re in Atlanta, you’ll most likely depart from:

  • Downtown Atlanta bus terminals – Often near Forsyth St SW, Mitchell St SW, or the broader downtown area
  • Some services may also use pickup points near major transit hubs or park-and-ride locations

Because bus providers can update routes and pickup spots, it’s wise to:

  • Check exact departure address when booking
  • Arrive 30–45 minutes early, especially if you’re not familiar with Downtown Atlanta streets

Who Bus Travel Works Well For

Bus service can be useful if:

  • You don’t have a car in Atlanta
  • You’re visiting Atlanta and want a side trip to Knoxville without renting a vehicle
  • You prefer not to drive in Atlanta traffic or mountain interstates

Bring a light jacket or layer for the bus (air conditioning can be strong), and keep snacks and water handy for the ride.

Flying From Atlanta to Knoxville

There are short flights from Atlanta to Knoxville, but whether it makes sense depends on your situation.

Airports Involved

  • Departure:

    • Hartsfield-Jackson Atlanta International Airport (ATL) – Main Atlanta airport, accessible by MARTA rail and major highways
  • Arrival:

    • McGhee Tyson Airport (TYS) – Serves the Knoxville area, located in Alcoa, TN, just south of Knoxville

What Atlanta Travelers Should Consider

  • The flight time is short—often under an hour in the air.
  • However, you’ll need to factor in:
    • Time to reach Hartsfield-Jackson from your home or hotel in Atlanta
    • Security screening and boarding time
    • Travel from McGhee Tyson Airport into Knoxville (rideshare, rental car, or local transport)

For many Atlanta residents, driving is just as fast door-to-door unless you already plan to connect through ATL for a longer trip or prefer to avoid highway driving altogether.

When Flying May Make Sense

  • You’re already at ATL due to another flight and tagging on Knoxville
  • You prefer air travel over long drives
  • You have limited time but are close to the airport and comfortable with quick turnarounds

Renting a Car in Atlanta for the Trip

If you’re visiting Atlanta and then going on to Knoxville, you may need a rental car.

Common rental locations:

  • Hartsfield-Jackson Atlanta International Airport – Centralized rental car center accessible by airport SkyTrain
  • Midtown, Downtown, Buckhead – Various rental offices, often near MARTA stations or major streets

Tips for renters:

  • Confirm that your rental agreement allows out-of-state travel (most major agencies do).
  • Ask about mileage policies if you expect to do additional driving beyond Atlanta–Knoxville–Atlanta.
  • If you’re not used to interstates with heavy truck traffic, request a vehicle you feel comfortable handling at highway speeds.

Weather and Seasonal Considerations

The Atlanta to Knoxville route crosses North Georgia and East Tennessee, which can experience different weather than central Atlanta.

Things to keep in mind:

  • Winter (Dec–Feb):

    • Atlanta may be mild while higher elevations near Chattanooga and East Tennessee can see snow or ice.
    • Check road conditions before you leave, particularly in cold snaps.
  • Spring and Summer:

    • Expect heavy rainstorms or thunderstorms, which can reduce visibility on I‑75 and I‑40.
    • Construction zones can be more active; watch for reduced-speed areas.
  • Fall:

    • Popular season due to foliage.
    • Traffic can be heavier on weekends, especially near mountain and park access points if you decide to detour toward the Smokies.

Atlanta-Based Planning Tips Before You Go

1. Use Local Transit or Rideshare to Reach Your Departure Point

If you’re leaving from Downtown Atlanta but don’t want to leave a car in paid parking:

  • MARTA Rail:

    • Red and Gold lines run through Midtown, Downtown, and to Hartsfield-Jackson.
    • Many Atlanta neighborhoods are within a short rideshare ride of a MARTA station.
  • Rideshare / Taxis:

    • A common choice if you live in intown neighborhoods like Inman Park, Old Fourth Ward, or West Midtown and are heading to a bus station or to a friend’s car.

2. Time Your Departure Around Atlanta Traffic Patterns

For most people living in or visiting Atlanta:

  • Leaving very early morning or late morning often feels least stressful.
  • If you must leave during rush hour, build in at least 30–45 extra minutes just to get clear of the core metro area.

3. Think About Your Return to Atlanta

When you drive back from Knoxville to Atlanta:

  • Afternoon or evening returns can bring you into Atlanta right during evening rush.
  • If you can, plan to arrive back in the city before 3 p.m. or after 7 p.m.

This applies especially if your destination is inside the Perimeter (I‑285), such as Midtown, Virginia-Highland, Grant Park, or Westside.

What to Pack and Prepare for the Trip

For most Atlanta to Knoxville trips, you don’t need anything unusual, but it helps to:

  • ✅ Keep a printed or downloaded map/route as a backup if phone signal is spotty
  • ✅ Pack water and snacks, especially if traveling with kids or pets
  • ✅ Bring phone charger and car mount if you’re driving
  • ✅ Carry light layers—Atlanta can be warmer than Knoxville, especially in cooler months

If you’re planning to explore outdoor areas or the Smoky Mountains from Knoxville, pack:

  • Comfortable walking shoes
  • Weather-appropriate layers and rain protection
  • Any permits or park info you may need

From Atlanta, the trip to Knoxville is close enough for a long day trip yet rich enough for a full weekend or longer stay. By choosing the right route—interstate for speed or scenic roads for exploration—and planning around Atlanta’s traffic rhythms, you can make the journey smooth, predictable, and comfortable.